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Sunday brings the initial Wear-Tyne derby since 2024, but which side will celebrate – Sunderland or the Magpies?
"For most of last season, no one would have predicted the Wearside club getting promoted and being competitive with Eddie Howe's Newcastle, never mind being above them in the table," stated analyst Chris Sutton.
"The situation is very different now, and the way they play makes me think they've got a real chance."
He is offering scoreline guesses for all 380 Premier League games this campaign, against AI, fans and a range of guests.
For week 16, he takes on England Gaming star Daniel 'Stingray' Ray.
Ray is vying for victory for the eLions – the Football Association's official esports team – at the gaming title European esports championship finals tournament, which will occur at Twickenham Stadium on Saturday.
You can watch Uefa's video platform, Instagram Live and short-form video channels, as well as the official Twitch channel and its YouTube counterpart and England's Twitch.
Are you in alignment with their predictions? You can make your own guesses below.
The most popular scoreline picked for each game is featured in the leaderboards at the bottom of this page.
Predicting the right outcome (selecting a win, draw or defeat) is worth 10 points. The exact score earns 40 points.
Ray, who competes for his club side and Manchester City as well as England, is making his debut at the eEuros finals after getting through the qualification rounds.
A group of eight will play for their countries at the finals in a knockout format, competing for a $100,000 prize pool and a highly sought-after spot in the global championship qualifiers, with the Danish representative Anders Vejrgang looking to retain the title he won last year.
"I am feeling really good for it," Ray said. "I have a really good coach alongside me and preparation has been going well.
"It is invariably an honour to play for your country. Of course when you are younger, you imagine doing it as an real-life footballer, but when you go into this field and there is an opportunity to represent England, putting the shirt on is something incredible.
"I defeated Vejrgang 9-4 in qualifying to get here. I've played against him recently just in practice, and in other tournaments before - but I'd not previously defeated him in a tournament before.
"In my opinion he is the top competitor in the world so getting a win over him in a tournament like this just provides a massive injection of confidence."
Premier League Predictions
Saturday, 13 December
Chelsea vs Everton
Stamford Bridge, 15:00 GMT
Chelsea were outstanding against the Gunners at the end of November, when they earned a stalemate after being reduced to 10 men, and I was thinking here we go, they could possibly be challengers for the crown.
In the matches following, however, they were beaten physically by Leeds, looked lethargic against Bournemouth and this week got defeated by Atalanta in the Champions League.
So manager Enzo Maresca is in need of a win here to get back on track, but it will be a challenge because the Toffees are such a dangerous team.
Kiernan Dewsbury-Hall and Iliman Ndiaye are playing really well and Everton have got a bit of a positive run at the moment.
On form you would likely back the visitors, while the most logical prediction would probably be a draw, but I'm throwing caution to the wind.
Chelsea haven't given me any good cause to back them recently, but I just have a feeling Chelsea will emerge victorious because they are at home and they are overdue a victory.
Sutton's prediction: 2-1
Stingray's prediction: With this being at the Bridge, I am going to back Chelsea. I think they will start off really well and go 2-0 up, then Everton will nick one back but then Chelsea score late. 3-1
AI's prediction: 2-0
Liverpool vs Brighton
Anfield, 15:00 GMT
I'm attending this game and it will be intriguing to see what we get from the Reds.
I am really pleased for Reds boss Arne Slot to get such a crucial result at Inter Milan on Tuesday after all the stuff with Mohamed Salah this week.
Slot shouldn't need to put up with that nonsense. I know Salah has been a icon for Liverpool but fundamentally Slot just wants to win games and there is nothing personal in his team selection.
They changed their tactical setup against Inter and went with a midfield diamond and two up top.
All the talk is going to be talking about whether Salah is included for this game, but the only way he is going to be brought back into the fold is if he makes amends.
Slot's primary concern will be on winning this game, but it is a challenging encounter.
It's fair to say it is the same for most teams but I find Brighton so hard to predict. I always feel they have got a goal in them, but they are quite open too.
The Merseysiders need to get back to a consistent run of form, but I am not sure how much their exertions at the San Siro will have affected their stamina.
I've selected a couple of Brighton players in my Fantasy Premier League side, so they will almost certainly blank - but I do think they can get something at Anfield.
Sutton's prediction: 2-2
Stingray's prediction: This is a game which is going to give Liverpool a bit more of their confidence back. Obviously they had a good win in midweek and they can build more momentum here. 2-1
AI's prediction: 3-1
Sunday, 14 December
Sunderland vs Newcastle
Stadium of Light, 14:00 GMT
The Black Cats have had the week off while Newcastle had to work so hard against Bayer Leverkusen on Wednesday, only to concede a late equaliser late on.
With the exception of their superb performance against Everton a couple of weeks ago, Newcastle's away form has been poor, especially straight after they've played in the Champions League.
The pattern suggests that tendency to continue on Sunday, and their fatigue is likely to be a factor in how this game goes because of Sunderland's high press.
We saw how incessant Regis le Bris's side are. They overpowered the Gunners, and it was incredible to watch.
Many pundits talks about how Granit Xhaka has been brilliant for the Black Cats, and he has been excellent, but Noah Sadiki, who plays in midfield with him, has also been one of the best acquisitions and should be recognised too.
I am expecting this being the best game|most exciting fixture